美国爱荷华大学招聘药理学博士后

Employer: The University of Iowa
Location: Iowa City, IA
Type: Other
Posted: July 08, 2011
Expires: September 06, 2011
Requisition number: 2198
job description

Institute Information

The University of Iowa
Department of Pharmacology, Carver College of Medicine
2-252 BSB, 51 Newton Road
Iowa City, IA, 52242
Website: http://

A NIH-funded postdoctoral position is available immediately to study the regulation of expression, trafficking, localization and functions of voltage-gated Na+ and ligand-gated TRP channels by diverse cellular signal transduction pathways that are initiated by factors released from tumor/microenvironment. The laboratory's research is geared towards thorough understanding of tumor-nerve crosstalk via neuronal ion channel modulations that underlie cellular plasticity and regulation of electrical excitability of neurons, in relation to cancer-induced pain and tumor-induced seizure conditions. The laboratory utilizes multidisciplinary approach, which include primary neuronal cultures/co-cultures, biochemical, cell/molecular biological, immunohistochemical and electrophysiological techniques, as well as diverse rodent behavioral assessments. The laboratory has its own tissue culture, biochemical, cell/molecular biological, electrophysiological, microscopy and rodent behavioral analysis facilities. In addition, the University of Iowa Carver College of Medicine has outstanding core research (microscopy & imaging, histopathological, genomic, proteomic and transgenic) facilities, for the rapid advancement of research work.

Qualification

Applicant must be highly motivated individual possessing a PhD or MD/PhD degree with training/experience in patch-clamp electrophysiology (preferably on Nav and/or TRP channels), as well as have very good knowledge in basic cell physiology, as evidenced from peer-reviewed research publications. Experience in intracellular or field potential recordings in brain/spinal cord slices, and any of the above-mentioned techniques will be an added advantage. Graduate students close to completing their doctoral degree in next couple of months are strongly encouraged to apply.

How to Apply

NIH scale (Annual - $38,496 + health care benefits)