美国福克斯•蔡斯癌症中心博士后招聘

A Postdoctoral Associate position, fully funded through a NIH R01 grant, is immediately available in the laboratory of Alfonso Bellacosa M.D., Ph.D. at the Fox Chase Cancer Center – Philadelphia, to study the role of base excision repair in mediating active DNA demethylation in mammals. Active DNA demethylation is emerging as an important mechanism of gene activation, as shown by recent studies conducted by our group (Cortellino et al. Cell 2011) and other laboratories. We are particularly interested in the role of DNA demethylation in development and cancer. The project will focus on the mechanisms and functional consequences of DNA demethylation, using biochemical, molecular and cellular biology techniques, as well as animal models. Previous experience with these techniques and mouse models is desirable.

The Fox Chase Cancer Center is consistently ranked as one of the best places to work for postdocs (The Scientist, 2011). The opportunity exists here to collaborate across many disciplines and build relationships with a well respected group of experts. Our institution boasts an impressive array of research facilities comparable to much larger institutions, including applications of the latest technology. Fox Chase Cancer Center is located in a quiet, park-like section of Philadelphia, but still very close to everything that this historic, yet vibrant city has to offer.

Prospective candidates (PhD or MD) should send a CV and up to three references to:
Alfonso.Bellacosa@fccc.edu

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