留学人才网 > 高校招聘 > 海外 >

德国欧洲分子生物学实验室结构生物学博士后岗

2011-10-14 15:33 来源: 未知 作者: 颜墨

 

Job Title: Postdoctoral Fellowship: Structural biology of RIG-I like helicases
Job Number: 4010070
Date Posted: 10/10/2011
Application Deadline: 11/6/2011
 

Job Description

The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world. The Headquarters Laboratory is located in Heidelberg (Germany) and the outstations are in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy).

The group of Stephen Cusack at the EMBL Grenoble Outstation is seeking to recruit a motivated post-doctoral fellow to work on the structural biology of RIG-I like helicases. These cytoplasmic signalling proteins are pattern recognition receptors of the innate immune system and are critical for the early detection of viral infections through recognition of non-self viral RNA molecular patterns, which triggers interferon production. The Cusack group has recently determined crystal structures of the auto-repressed and RNA/ATP activated states of RIG-I leading to the first structure-based model of the RIG-I activation mechanism. This work is in press in Cell. Future work will refine this model and extend structural work to the two other RIG-I like helicases, MDA5 and LGP2 and the downstream signalling partner MAVS.
The EMBL Grenoble Outstation is embedded in the Grenoble Partnership for Structural Biology (PSB), which is a uniquely rich environment for structural biology providing access to state-of-the-art facilities for protein production, biophysical characterisation, crystallisation and structure determination (ESRF synchrotron, NMR, EM).
Candidates should have a PhD and a record of successfully working on challenging structural biology problems. Experience in some of the following will be an advantage: protein expression in insect cells, in vitro production of RNA and reconstitution of protein-RNA complexes, synchrotron based protein crystallography. Candidates interested in biophysical mechanistic studies of RLHs in vitro or in living cells (e.g. by fluorescence techniques) are also encouraged to apply. Funding is available for an initial two year period with the possibility of staying up to five years.
    EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation.    
Contact: HR Officer
HR Recruitment
EMBL (European Molecular Biology Laboratory)
Meyerhofstrasse 1
Heidelberg, 69117
Germany
Employer's Web Site: Visit employer's website

Online Application:

 

Apply for this job from Employer's website

 中国留学人才网（海归人才网）www.liuxuehr.com 为广大海外高层次人才提供回国就业、创业机会，关注海归生活。海归QQ群：106247053

    声明：凡本网注明"来源：XXX"的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。

    相关文章

    海归QQ群

    申请加群请以“留学国家-目前所在地”格士发送请求，群有人数上限，每人只能加一个群。
    海归部落千人群
    63984971    		 海归部落2号群
    103237942    		 上海海归人才2号群
    461068872    		 北京海归人才群
    63984971
    上海海归人才群
    103237942    		 天津海归人才群
    461068872    		 重庆海归人才群
    172719654    		 山东海归人才群
    462302845
    江苏海归人才群
    172331746    		 浙江海归人才群
    314125833    		 江西海归人才群
    463247306    		 福建海归人才群
    457497619
    安徽海归人才群
    457823891    		 河南海归人才群
    264015004    		 湖北海归人才群
    109623634    		 湖南海归人才群
    458690950
    广东海归人才群
    432013578    		 海南海归人才群
    312160331    		 黑龙江海归人才群
    312929192    		 吉林海归人才群
    313316571
    辽宁海归人才群
    109899038    		 河北海归人才群
    282994183    		 陕西海归人才群
    315357786    		 甘肃海归人才群
    315753165
    宁夏海归人才群
    517762915    		 青海海归人才群
    319457961    		 四川海归人才群
    517765170    		 云南海归人才群
    432350311
    贵州海归人才群
    517766496    		 广西海归人才群
    517767217    		  

    扫描二维码，关注留学人才网微信公众号

    高层次人才招聘